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    • Main Text The field of stem cell

    2018-10-24

    Main Text The field of stem cell research has continued to advance at a terrific pace over the past year, with continued improvements in technology allowing us to interrogate the pathways underpinning development, injury, and repair of our cells, tissues, and organs. We have seen leaps forward in the translation of these advances into preclinical and clinical research. The International Society for Stem Cell Research (ISSCR) is committed to providing voice and visibility to this progress and to the global stem cell research EHop-016 driving these efforts. This journal, Stem Cell Reports, launched just two years ago by the ISSCR, is an important part of this commitment. Stem Cell Reports has reflected progress in the field, developing quickly to provide a high visibility platform for scientific and medical discovery and building on the organization’s Annual Meetings and International Symposia. Over the past year, it has been very rewarding to see the breadth and quality of research included in Stem Cell Reports. With reproducibility vital to the progress of the field, I commend the commitment to review and publish studies that debate or confirm existing literature. I would like to take this opportunity to recognize the driving force behind this success, the strong editorial leadership provided by our Editor in Chief Christine Mummery and Associate Editors Nissim Benvenisty, Thomas Graf, Hideyuki Okano, and David Scadden, and the support from Managing Editor Yvonne Fischer and the teams at ISSCR headquarters and our publishing partner, Cell Press. Sharing our excitement in the field in an accurate and balanced way plays an important role in this enterprise, building trust and garnering public support. In parallel with efforts for professional guidance, the ISSCR has focused over the past year on the launch of a new and expanded Closer Look at Stem Cells website (http://www.closerlookatstemcells.org). The website is a cornerstone in the society’s ongoing commitment to public education and outreach, engaging visitors in stem cell science and sparking their interest in the progress of stem cell research across the globe. The new-look site presents informational pages on basic stem cell biology, research, and clinical translation processes and provides deeper information on clinical trials and the use of stem cells in understanding specific health conditions—macular degeneration, multiple sclerosis, heart disease, and diabetes—with more pages planned. It includes the “Stem Cells in Focus” blog, which aims to makes cutting-edge research exciting and accessible to non-scientists. We encourage you to visit the site and to look out for an upcoming article in this journal by the task force behind this project that will speak to the underlying issues that drive the need for this site, considerations in developing the content, and the role each of us can play. We hope you will point to the Closer Look website in your conversations with the public and share it with your colleagues, research institutions, and other organizations with which you are affiliated. To accompany the award celebrations, in this issue of Stem Cell Reports, we are delighted to present review articles from the past year’s prizewinners. Azim Surani, Wellcome Trust/Cancer Research UK Gurdon Institute, winner of the 2014 McEwen Award for Innovation, reviews our current understanding of germline development and the extension of these paradigms to other areas of research (Surani, 2015). Valentina Greco, Yale University, winner of the 2014 ISSCR-BD Biosciences Outstanding Young Investigator Award, reviews her laboratory’s continued exploration of the interdependency of the skin stem cell and its niche (Mesa et al., 2015). Finally, we hope that you enjoy the research contained within this issue, in addition to past and future issues. Stem Cell Reports continues to reflect the energy and advancement in the field, and we hope that you are as excited as we are about what the next year will bring.