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The development in high income countries shows the possibili
2019-04-23
The development in high-income countries shows the possibilities for progress in twin health and survival: Danish twins born between 1870 and 1900 had higher early-life mortality rates than twins born in the late 20th century and contemporary sub-Saharan twins, with about 40% under-6 mortality (doub
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dna synthesis inhibitors Long QT syndrome LQTS a rare
2019-04-23
Long QT syndrome (LQTS), a rare inheritable arrhythmia first described by Romano and Ward et al. in the 1960s, is characterized by the prolongation of the QT interval on surface ECGs and an increased risk of potentially fatal ventricular arrhythmias, especially torsade de pointes . In 1995, after ye
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br LEGADO FUJIMORISTA No seu segundo mandato Garc a abandono
2019-04-22
LEGADO FUJIMORISTA No seu segundo mandato, García abandonou as veleidades esquerdistas realizando um governo abertamente neoliberal. Embora em campanha criticasse o modelo de exploração mineira em que se assentava o crescimento peruano, praticamente eximindo as empresas de obrigações tributárias
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Graft versus host disease prophylaxis included
2019-04-22
Graft versus host disease prophylaxis included tacrolimus, mycophenolate mofetil and post transplant cyclophosfamide (50mg/kg on days +3 and +4) as previously proposed by Baltimora׳s group. After a follow up of 18 months patient is in good clinical conditions, in persisting complete remission as es
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Premature deaths of women have profound effects
2019-04-22
Premature deaths of women have profound effects on families, societies, and economies, regardless of the age at which they occur and whatever the cause, including an—often preventable—NCD or injury later in life. Families, especially if female-headed, are driven into poverty through catastrophic hea
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br Genetic basis Similar to other arrhythmia syndromes Bruga
2019-04-22
Genetic basis Similar to other arrhythmia syndromes, Brugada and early repolarization syndromes are inherited diseases that are usually transmitted in an autosomal-dominant manner [26]. To date, 13 genes have been associated with Brugada syndrome. Loss-of-function mutations in SCN5A, encoding the
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Introduction Despite advances in the
2019-04-22
Introduction Despite advances in the treatment of early stage breast cancer, bone remains the most common site of distant metaformin [1]. The consequences of bone metastases include reduced survival, morbidity, pain and reduced quality of life [2]. While the care of these patients is multidiscipli
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EAI045 Assim pensamos que os discursos analisados neste arti
2019-04-22
Assim, pensamos que os discursos, analisados neste artigo, construídos pelos intelectuais colaboradores de Araucaria de Chile e difundidos pela revista, ao ressaltarem duas vitoriosas revoluções armadas latino-americanas, exatamente no período de vigência da prpm, dialogaram, de alguma maneira, com
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Se antes Jos Mart em Cuba em
2019-04-22
Se antes José Martí em Cuba, em 1891, com Nuestra América, e logo, em 1900, José Enrique Rodó com Ariel, propugnavam uma alteridade diversa dos Estados Unidos para os latino-americanos pós-independência, por exemplo, Dipesh Chakrabarty, em Provincializing Europe, reelaborou essas e aquelas consignas
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The mechanism leading to the gelatinous transformation may i
2019-04-22
The mechanism leading to the gelatinous transformation may involve inhibition of tyrosine kinase activity by tyrosine kinase inhibitors (TKI) leading to blockage of downstream signal pathways, affecting extracellular matrix deposition, adipocyte differentiation and angiogenesis. Moreover, the catabo
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Since many decades bone tumours have stimulated imagination
2019-04-20
Since many decades, bone tumours have stimulated imagination of researchers and numerous therapeutic alternatives have been proposed [134,135, Fig. 4]. The better knowledge of OPG/RANK/RANKL system leads to the development of peptides mimicking OPG and blocking RANK–RANKL interactions [136–139]. Inh
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Cost effectiveness is another major concern for
2019-04-20
Cost effectiveness is another major concern for the governments in countries with public health system. Van-den Hout WB et al. at Netherlands [7] did a cost utility analysis showing the cost of radiation treatment including re-treatment for bone metastases using SF versus MF were €2438 versus €3311
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br Discussion The present meta analysis of randomized
2019-04-20
Discussion The present meta-analysis of randomized trials demonstrated that treatment with AAMs is associated with an increase in non-cardiac and all-cause mortality as compared to non-arrhythmic therapy or control group. There was no significant reduction in cardiac or arrhythmic mortality betwe
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br Aunque mucho se ha escrito acerca de
2019-04-20
Aunque mucho se ha escrito acerca de los propósitos que persigue Max Aub al concebir y desarrollar la operación Jusep Torres Campalans, para Nelken la cosa no admite dudas: nos hallamos frente nadph oxidase una burda comedia del arte de vanguardia, ante una cruel banalización de aquella “etapa her
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Fourth the enormous investment in
2019-04-20
Fourth, the enormous investment in accessible medicines and medical products without investment in checking their quality is profoundly illogical. WHO estimates that only 7% of sub-Saharan countries had a “moderately functioning MRA”. We cannot expect the world\'s medicine supply to improve without
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