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To the best of our knowledge only
2019-04-24

To the best of our knowledge, only one other group studied low-dose protracted oral clofarabine in MDS patients who failed hypomethylating agents. They studied 5mg (fixed dose) daily for 10 consecutive days of a 28-day cycle. All patients who were treated for 10 days had a greater than 25% drop in t
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Predicting the potential effects of climate
2019-04-23

Predicting the potential effects of climate change on the incidence and distribution of infectious gastroenteritis can assist public health providers to control and prevent severe outbreaks in the future. Implementation of programmes for rotavirus vaccination clearly shows benefit and should be an t
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br Clinical characteristics Brugada syndrome is more common
2019-04-23

Clinical characteristics Brugada syndrome is more common in Southeast Asia, including Japan, with an estimated prevalence of 12 in 10,000 individuals, compared with Western countries where the estimated prevalence is 1 to 5 in 10,000 individuals. However, the incidence of early repolarization syn
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Since BM impairs the balance between bone formation and
2019-04-23

Since BM impairs the balance between bone formation and bone resorption, altered bone remodeling activities can be assessed directly by measuring the components of affected bone cells or indirectly by analyzing metabolic products released from the bone matrix by changed rates of bone formation or re
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El proceso hist rico de conformaci n del
2019-04-23

El proceso histórico de conformación del Estado en Chile, su momento constitutivo en el siglo xix es precisamente la invasión del Estado liberal chileno a territorio de los pueblos originarios; desposesión que disocia la comunidad cultural mapuche de la soberanía territorial que hasta ese momento ha
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order MC1568 The patient was consented to treatment on clini
2019-04-23

The patient was consented to treatment on clinical trial NCT02527447 and received treatment with salvage chemotherapy of mitoxantrone 12mg/m2/day IV on days 1–3, etoposide 200mg/m2/day continuous IV infusion (CIV) on days 8–10, and cytarabine 500mg/m2/day CIV on days 1–3 and 8–10 (EMA). Infectious p
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With the availability of vaccines screen and
2019-04-23

With the availability of vaccines, screen-and-treat approaches, and effective drugs to treat hepatitis C virus, , and HIV infections, the question is no longer limited to what to do but now extends to how to implement. The expanding focus from basic research, drug development, and clinical trials th
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The development in high income countries shows the possibili
2019-04-23

The development in high-income countries shows the possibilities for progress in twin health and survival: Danish twins born between 1870 and 1900 had higher early-life mortality rates than twins born in the late 20th century and contemporary sub-Saharan twins, with about 40% under-6 mortality (doub
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dna synthesis inhibitors Long QT syndrome LQTS a rare
2019-04-23

Long QT syndrome (LQTS), a rare inheritable arrhythmia first described by Romano and Ward et al. in the 1960s, is characterized by the prolongation of the QT interval on surface ECGs and an increased risk of potentially fatal ventricular arrhythmias, especially torsade de pointes . In 1995, after ye
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br LEGADO FUJIMORISTA No seu segundo mandato Garc a abandono
2019-04-22

LEGADO FUJIMORISTA No seu segundo mandato, García abandonou as veleidades esquerdistas realizando um governo abertamente neoliberal. Embora em campanha criticasse o modelo de exploração mineira em que se assentava o crescimento peruano, praticamente eximindo as empresas de obrigações tributárias
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Graft versus host disease prophylaxis included
2019-04-22

Graft versus host disease prophylaxis included tacrolimus, mycophenolate mofetil and post transplant cyclophosfamide (50mg/kg on days +3 and +4) as previously proposed by Baltimora׳s group. After a follow up of 18 months patient is in good clinical conditions, in persisting complete remission as es
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Premature deaths of women have profound effects
2019-04-22

Premature deaths of women have profound effects on families, societies, and economies, regardless of the age at which they occur and whatever the cause, including an—often preventable—NCD or injury later in life. Families, especially if female-headed, are driven into poverty through catastrophic hea
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br Genetic basis Similar to other arrhythmia syndromes Bruga
2019-04-22

Genetic basis Similar to other arrhythmia syndromes, Brugada and early repolarization syndromes are inherited diseases that are usually transmitted in an autosomal-dominant manner [26]. To date, 13 genes have been associated with Brugada syndrome. Loss-of-function mutations in SCN5A, encoding the
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Introduction Despite advances in the
2019-04-22

Introduction Despite advances in the treatment of early stage breast cancer, bone remains the most common site of distant metaformin [1]. The consequences of bone metastases include reduced survival, morbidity, pain and reduced quality of life [2]. While the care of these patients is multidiscipli
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EAI045 Assim pensamos que os discursos analisados neste arti
2019-04-22

Assim, pensamos que os discursos, analisados neste artigo, construídos pelos intelectuais colaboradores de Araucaria de Chile e difundidos pela revista, ao ressaltarem duas vitoriosas revoluções armadas latino-americanas, exatamente no período de vigência da prpm, dialogaram, de alguma maneira, com
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