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br The follow up clinic
2019-06-27
The follow-up clinic These trial results have significant implications for clinic efficiencies. The safe and effective replacement of the bulk of “routine” in-clinic evaluations demonstrated in TRUST (Fig. 3) has a huge implication for resource utilization. Although demanding adjustment to differ
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An incisional biopsy was undertaken
2019-06-27
An incisional biopsy was undertaken. Peri-operative examination of the lesion revealed an expansile tumor mass brownish in color with focal whitish areas (Fig. 3). The lesion could be delineated from the surrounding cortical bone, and surrounding soft tissues. Histopathologically the biopsy material
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Introduction The heart beat provides the mechanical force fo
2019-06-27
Introduction The heart beat provides the mechanical force for the pumping of oxygenated blood to, and deoxygenated blood away from, the peripheral tissues [1]. This depends critically on the orderly activation and recovery of electrical excitation through the myocardium. Disruptions of this can lea
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Human ether a go go related gene HERG encodes the
2019-06-27
Human-ether-a-go-go-related gene (HERG) encodes the α-subunit of rapidly-activating delayed-rectifier potassium ion channel that generate IKr. This outward potassium current is elicited during the plateau phase of action potentials and is required for repolarization [4]. After being translated in th
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br An understanding of the global health burden
2019-06-27
An understanding of the global health burden of sex work, including sex trafficking and transactional sex, is urgently needed to direct resources to very large and vulnerable populations. Estimation of this burden will be a challenge, but similar efforts have been undertaken in other populations a
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Si bien en Argentina la democracia
2019-06-27
Si bien en Argentina la democracia se alcanzó por el colapso de la dictadura, la guerra de Malvinas, la misma estaba planifi en las “Bases para la Intervención de las Fuerzas Armadas en el Proceso Nacional”. En este documento se indicaba que el proceso se desarrollaría mediante la ejecución de tres
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ceramide of As condi es desta reinser o seriam consolidadas
2019-06-27
As condições desta “reinserção” seriam consolidadas ceramide of partir do chamado “autogolpe”, quando Fujimori fechou o congresso e interveio no poder judicial em abril de 1992, decretando à moda argentina um “Gobierno de emergencia y reconstrucción nacional”. Em uma perversão da democracia, o presi
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br Case report We report
2019-06-27
Case report We report a case of an 18 year-old Caucasian male who was found to have thrombocytopenia at birth, with a platelet count of 58,000/mm3. Bone marrow biopsy was first performed in 1993, at 13 months of age, and showed 70–80% cellular marrow with occasional megakaryocytes and no evidence
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br Methods br Results Globally CCI increased by percent poin
2019-06-27
Methods Results Globally, CCI increased by 0·82 percent points a year, from 54·8% in 1994, to 71·2% in 2014 (CCI estimates at national level, stratified by wealth quintiles and place of residence, are presented in the appendix, pp 6–15). This gain was largely driven by low-income countries, wh
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br Discussion Bone marrow fibrosis is known to be associated
2019-06-26
Discussion Bone marrow fibrosis is known to be associated with hematolymphoid malignancies such as acute leukemia, Hodgkin and non-Hodgkin lymphoma. Among the acute leukemias, marrow fibrosis is most often seen with acute megakaryoblastic leukemia. It is an uncommon finding in APL and till date o
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Introduction Acute acalculous cholecystitis ACC is defined a
2019-06-26
Introduction Acute acalculous cholecystitis (ACC) is defined as an acute necroinflammatory disease of the gallbladder in the absence of cholelithiasis and has a multifactorial pathogenesis [1]. ACC has very rarely been described in patients undergoing myelosuppressive chemotherapy for acute myelobl
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br We have reviewed the issues and arguments presented by
2019-06-26
We have reviewed the issues and arguments presented by Wang et al. In fact, we have well-clarified these issues in “Discussion” section of our original article. The aim of our study was to investigate the expression of maternal antineuronal hedgehog inhibitor and their role in childhood autism s
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br Conclusion br Conflict of interest
2019-06-26
Conclusion Conflict of interest Introduction The implantable cardioverter-defibrillator (ICD) has dramatically reduced the risk of sudden death in patients with malignant ventricular tachyarrhythmias [1,2]. However, 10–30% of patients who have undergone ICD implantation experience “electric
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br A KCNJ mutation corresponding to
2019-06-26
A KCNJ8 mutation, corresponding to an S422L mutation in the protein, was first identified in a 14-year-old girl with early repolarization [59], who suffered frequent VF attacks. KCNJ8 encodes Kir6.1, which has 2 transmembrane regions, and the KATP channel is composed of a complex of Kir6.1 or Kir6
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br Case report A year old female presented with
2019-06-26
Case report A 50-year-old female presented with splenomegaly (24 cm) and pancytopenia in Mar. 2014. A bone marrow biopsy revealed hypocellular marrow (1st CFTRinh-172 of of R-COP (Fig. 3). Further 5 cycles of cytotoxic therapy with standard dose R-CEOP (rituximab; cyclophosphamide; epirubicin; v
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